Middle-aged man checking his watch during an outdoor workout.
Men's testosterone care

Feel more
like yourself.

Understand your testosterone. Explore a personalized plan for your energy, strength, and sex drive—with lab testing and a provider who knows your goals.

$79per month for the first 3 monthsUse code FIRST100Initial full-panel labs $50 at Quest or LabCorp

Start TRT GET LABS

$79/month for the first 3 months with code FIRST100. Initial full-panel labs $50. For eligible men 25+. Treatment requires provider approval.

Provider-guided careQuarterly labs includedFree shipping + suppliesOngoing support
A clearer picture of your health

Your symptoms matter.
So do your numbers.

Feeling less like yourself can show up in the bedroom, at the gym, or in the middle of an ordinary day. Low testosterone may be part of the picture—but symptoms alone don't tell the whole story.

Nucore brings your health history, biomarkers, and goals together. You meet with a provider to understand your results and decide whether testosterone or enclomiphene is right for you.

Check availability
Your goals are the starting point

More of what
matters to you.

Tell us what you want to feel, do, and get back to. Your provider helps you understand where hormone care may fit.

Smiling middle-aged man in a black workout shirt standing in a gym.
Strength & body composition

Feel stronger
in your everyday.

For men with confirmed low testosterone, treatment may support lean body mass. Your activity, nutrition, and overall health remain part of the plan.

Couple standing close together with their foreheads touching beside a window.
Sex drive & connection

Make room
for connection.

TRT may improve sex drive and sexual function when low testosterone is contributing to symptoms.

Man in a white athletic shirt resting with his hands on his knees after a run.
Energy & how you feel

Understand
your low energy.

Fatigue can have many causes. Lab testing and a provider review help you find the next step; energy improvements with TRT vary.

Explore my options

Potential benefits vary. These images illustrate goals, not patient outcomes.

The science behind the shift

Testosterone can
change with age.

Researchers observed average yearly declines of about 1.6% in total testosterone and 2–3% in bioavailable testosterone.

Age is only one factor. Health, sleep, medications, and body composition also matter. Testing helps you understand your own picture.

Total testosteroneThe total amount circulating in your blood.
Free testosteroneThe small portion that isn't attached to proteins.
Bioavailable testosteroneFree testosterone plus testosterone loosely attached to albumin.
Testosterone through the years
Total testosteroneFree & bioavailable: illustrative range
Illustrative testosterone change with ageAll measures are indexed to 100 at age 40. Orange line models a 1.6 percent annual decline in total testosterone; the brown band illustrates a 2 to 3 percent annual decline in free and bioavailable testosterone. Values are a visualization of published average rates, not measured age-group results or a prediction for an individual.025507510040455055606570Age (years)Relative level (age 40 = 100)

Illustration from reported average annual rates, indexed to age 40 = 100. Not measured age-group averages, a diagnosis, or a forecast of your levels.

Listen to what your body is telling you

Could low testosterone
be part of the picture?

These changes are worth discussing with a provider—especially when several happen together.

Lower sex drive

Less interest in sex, fewer spontaneous erections, or trouble getting or keeping an erection.

Less energy

Persistent fatigue or a noticeable drop in your usual get-up-and-go.

Changes in strength

Loss of muscle or strength, sometimes alongside changes in body composition.

Mood & focus changes

Feeling down, more irritable, or finding it harder to concentrate.

Fertility concerns

Low sperm count, trouble conceiving, or changes in testicular size.

Other physical signs

Reduced body hair, breast tenderness or enlargement, weaker bones, anemia, or hot flashes when levels are very low.

These symptoms can have many causes. A diagnosis usually requires symptoms plus consistently low testosterone on two separate early-morning blood tests. Your clinician may order additional testing to understand why levels are low.

Two approaches. One personalized plan.

Find the right fit
for your body.

Your labs, symptoms, health history, and fertility goals help guide the choice.

Illustrative Nucore testosterone vial packaging.
Testosterone replacement therapy

Testosterone

Replaces testosterone when your body isn't making enough and treatment is medically appropriate.

  • A prescription tailored to your needs
  • Follow-up labs to guide adjustments
  • Medication, supplies, and free delivery

TRT can reduce sperm production. Tell your provider if having children now or in the future is important to you.

Illustrative Nucore enclomiphene oral medication packaging.
An oral alternative to replacement

Enclomiphene

Helps stimulate your body's own testosterone production in selected men with low testosterone.

  • An oral prescription option
  • May help maintain sperm production
  • Provider review and ongoing monitoring

Enclomiphene is not FDA-approved. Fertility and symptom improvements are not guaranteed; your provider will explain benefits, uncertainties, and risks.

Find your treatment path

Packaging shown is illustrative. Your prescription and dispensed packaging may differ.

How Nucore works

From answers
to a plan that fits.

Lab testing first. A real-time provider visit. Continued care as your needs change.

Step 01

Complete your survey

Share your symptoms, medical history, medications, and what you'd like to improve.

Step 02

Check your biomarkers

Complete your initial full-panel labs for $50 at Quest or LabCorp. Your provider uses your results to assess your hormone health.

Step 03

Meet with your provider

Schedule a live visit to review your goals and labs, ask questions, and build your plan together.

Step 04

Care arrives at your door

If approved, your medication is ordered and shipped free with supplies and ongoing support.

Illustrative screens with sample lab data and care-team messages.

Your plan evolves
with you.

Quarterly lab checks and scheduled provider follow-ups are included at no extra fee. Your medication is adjusted to your results and how you're feeling. A comprehensive annual panel replaces the fourth quarterly panel.

Nucore testosterone vial with pale blue cap.
Sexual wellness
Lean muscle support
Mood support
Personalized care
Potential benefits vary. Illustrative packaging.
Your health. Your pace.

Guided by your labs.
Shaped around you.

01

A dose that fits your needs

Your provider considers your bloodwork, symptoms, health history, and goals to choose your treatment and follow-up plan.

02

Progress that matters to you

For men with confirmed low testosterone, TRT may support sexual wellness, lean body mass, and mood. Energy and focus improvements are less predictable.

03

Care that keeps adapting

Quarterly labs at Quest or LabCorp and scheduled provider reviews help guide adjustments as your levels and symptoms change.

Explore my treatment options

Treatment requires provider approval. Outcomes differ for each person.

Middle-aged man with a relaxed smile in a softly lit space.
The people behind your plan

Care that stays
with you.

Real conversations. Clear next steps. A treatment plan that grows with your goals.

Meet your provider, live

Review your labs, share what you want to improve, and ask your questions in a scheduled video visit.

Keep moving forward

Quarterly monitoring, thoughtful adjustments, and ongoing care team support are part of your program. Medication and supplies ship free.

Find my path with Nucore
Straightforward pricing

One program.
Care that continues.

Your prescription is just one part of the plan. Nucore includes the follow-through: labs, provider reviews, supplies, delivery, and ongoing support.

  • Personalized prescription, if approved
  • Quarterly labs and scheduled follow-ups
  • Medication adjustments when appropriate
  • Free shipping and supplies
  • Ongoing care team support
Your first 3 months
$79/month

For the first 3 months with code FIRST100. Eligibility and prescribing requirements apply.

Initial labs · full panel$50

Quarterly monitoring labs are included in the program—no extra lab fees.

Check my state & get started

Initial lab fee is separate from program pricing. Completing labs does not guarantee a prescription.

Featured in
Good questions. Clear answers.

Curious about TRT?
Start here.

You deserve to understand your options before you start.

Explore care with Nucore
Which hormone treatments can I explore with Nucore?
Nucore offers testosterone replacement therapy and oral enclomiphene. TRT replaces testosterone; enclomiphene can encourage your body to produce more of its own in selected men. Your provider helps choose an approach based on your labs, health history, and fertility goals. Enclomiphene is not FDA-approved, and your provider will explain its evidence and limitations.
What happens after I get started?
Complete your health survey, then have your initial labs drawn at Quest or LabCorp. Once your results are available, schedule a live visit with a provider to review your goals and lab results. If treatment is approved, your medication and supplies ship free to your door. Quarterly labs, follow-up visits, and appropriate medication adjustments are part of your program.
Will I need health insurance?
No insurance is required. Nucore's TRT program is self-pay. Your first 3 months are $79 per month with code FIRST100. Initial full-panel labs are $50. Quarterly monitoring labs are included at no extra fee.
Where will I have my bloodwork done?
Your lab testing is completed at Quest or LabCorp. Nucore provides the lab order and instructions so you can arrange your blood draw at a convenient Quest or LabCorp location. Follow your care team's directions about timing and preparation. Initial full-panel labs are $50, and quarterly monitoring labs are included in your program at no extra fee.
What benefits are realistic to expect?
In men with confirmed low testosterone, TRT may improve sex drive and sexual function. Some also notice improvements in mood or body composition. Energy and focus do not improve for everyone. Your provider helps you set realistic goals and reviews whether treatment is helping you.
What should I know about side effects?
Your provider reviews the risks before you start, and follow-up labs help monitor treatment. TRT can cause acne, fluid retention, higher blood pressure, or increased red blood cells; it can also lower sperm production and worsen sleep apnea in some men. Enclomiphene may cause headache, nausea, or visual changes, and its long-term safety is less established. Contact your care team about new or bothersome symptoms, particularly vision changes or swelling. Chest pain, sudden shortness of breath, or one-sided leg swelling require urgent medical care.
What if having children is part of my future plans?
Bring this up before starting. TRT can suppress sperm production. Enclomiphene may be an option for selected men because studies have shown preservation of sperm counts, but it does not guarantee fertility. Your provider can help you understand which evaluation and treatment path fits your goals.
Are follow-up labs and medication adjustments included?
Yes. Quarterly lab checks and scheduled provider follow-ups are included at no extra fee. A comprehensive annual panel replaces the fourth quarterly panel. Your provider reviews your results and how you feel, then adjusts medication when clinically appropriate. Supplies, free shipping, and ongoing support are also included.

Sources

Age-related testosterone changes — Feldman et al. (2002)

Feldman HA et al. J Clin Endocrinol Metab. 2002;87(2):589–598.

Read study on PubMed ↗
Androgen deficiency in middle-aged and older men

Araujo AB et al. 2004.

Read study on PubMed ↗
Effects of testosterone treatment in older men

Snyder PJ et al. N Engl J Med. 2016;374:611–624.

Read study on PubMed ↗
Enclomiphene, testosterone production and sperm counts

Kim ED, McCullough A, Kaminetsky J. BJU Int. 2016;117(4):677–685.

Read study on PubMed ↗
Testosterone restoration with enclomiphene

Wiehle RD et al. BJU Int. 2013;112(8):1188–1200.

Read study on PubMed ↗
Cardiovascular safety of testosterone-replacement therapy

Lincoff AM et al. N Engl J Med. 2023.

Read study on PubMed ↗
Your next step starts with answers

Get to know your levels.
Get a plan for you.

Start with your survey and initial full-panel labs for $50. Your provider will help you understand your results and decide what comes next.

Check availability & get started
Care where you live

Is Nucore TRT
available in your state?

Select your state to check our current service area. Our men's hormone program is for adults age 25 and older.

Choose a state to see availability.

Availability can change. Your provider confirms eligibility and the treatment options available to you.

Prescription treatment requires evaluation and approval by a licensed provider. Results vary. This page provides general education, not a diagnosis or a promise of results. Illustrative photography, packaging, and sample lab values do not depict a patient or a treatment outcome.